Leucoderma, also known as vitiligo, is a rare skin disease characterized by white spots and patches. When it occurs without any preceding disease it is called Vitiligo. Leucoderma is called ‘Shivtra’ in Ayurveda. Under this skin condition, certain parts of the skin gradually lose color leaving behind white patches. It may begin with a small patch but slowly and steadily spreads throughout the body. The main causes of leucoderma are said to be excessive mental worry, chronic or acute gastric disorders, and impaired hepatic function such as jaundice, worms or other parasites in the alimentary canal, typhoid, and burn injuries. According to Ayurveda, Leucoderma is caused due to the aggravation of Pitta Dosha. Aggravated Pitta leads to accumulation of ama (toxins) in deep layers of the skin, leading to the condition of Leucoderma. Ayurveda has the safest treatment option for vitiligo. Ayurvedic cure for vitiligo is governed by combination of rare and unique herbs.